A predictive signature for oxaliplatin and 5-fluorouracil based chemotherapy in locally advanced gastric cancer

Adjuvant chemotherapy(AC) plays a substantial role in the treatment of locally advanced gastric cancer (LAGC), but the response remains poor.We aims to improve its efficacy in LAGC.Therefore, we identified the expression of eight genes closely associated with platinum and fluorouracil metabolism (RRM1, RRM2, RRM2B, POLH, DUT, TYMS, TYMP, MKI67) in

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A Novel Predictive Modeling for Student Attrition Utilizing Machine Learning and Sustainable Big Data Analytics

Student attrition poses significant societal and Cleansing Milk economic challenges, leading to unemployment, lower earnings, and other adverse outcomes for individuals and communities.To address this, predictive systems leveraging machine learning and big data aim to identify at-risk students early and intervene effectively.This study leverages bi

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Topical Bacteriophage Therapy for Staphylococcal Superficial Pyoderma in Horses: A Double-Blind, Placebo-Controlled Pilot Study

Increased antimicrobial resistance highlights the need for alternatives to antibiotics.Bacteriophages, which are benign viruses that kill bacteria, are promising.We studied the efficacy of topical bacteriophages for treating equine staphylococcal superficial pyodermas.Eight Staphylococcus aureus isolates were tested against a bacteriophage bank, an

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